Chinese Journal of Plastic and Reconstructive Surgery

2021, v.3(02) 95-102

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Electric Field: A Key Signal in Wound Healing
Electric Field: A Key Signal in Wound Healing

Naixin JIA;Jinrui YANG;Jie LIU;Jiaping ZHANG;

摘要(Abstract):

Wound healing is a complex biological process that involves proliferation, migration, and differentiation. Endogenous electric field(EF)-directed migration of keratinocytes(galvanotaxis) is an essential step in wound re-epithelialization. Endogenous EFs are generated instantaneously after an injury because of the collapse of transepithelial potentials. The application of exogenous EF has become increasingly widespread in promoting wound healing, leading to a paradigm shift in patient outcomes. Here, we summarize the role and value of EF in wound healing through a review of the current research.

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基金项目(Foundation): supported by the National Nature Science Foundation of China (NSFC no. 81873936)

作者(Author): Naixin JIA;Jinrui YANG;Jie LIU;Jiaping ZHANG;

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